SUN LAB

RESEARCH FOCUS

The Sun Lab studies fundamental mechanisms of tissue formation, maintenance, function/dysfunction, regeneration/degeneration. We employ cutting edge genome editing, single cell transcriptomic and epigenomics, and whole-tissue clearing and advanced imaging approaches to delineate the robust programs that dictate normal biology, and uncover the imperfections that initiate pathogenesis.

At the center of our investigation is the lung, an organ that is vital for survival at first breath. It is the setting for many fetal, pediatric and adult diseases that have little explanation and no cure. We use disease modeling as a starting point to make basic science discoveries in developmental biology, stem cell biology, lung-immune-neural circuit interactions.